Suyash P. Awate Suyash P. Awate
Asha and Keshav Bhide Chair Professor
Computer Science and Engineering Department, Indian Institute of Technology (IIT) Bombay
Office: A-214, Kanwal Rekhi Building
Email: my-first-name
Research Publications Teaching Students CV Personal
Brain Tissue Segmentation via MRI
Suyash P. Awate, Tolga Tasdizen, Normal Foster, Ross T. Whitaker
Adaptive Markov modeling for mutual-information-based, unsupervised MRI brain-tissue classification
Medical Image Analysis 2006, 10(5):726-39

1) noise
2) oversmoothing in cortex
3) field inhomogeneity
4) partial-volume effects

Our Approach
1) Markov random field model on data; inferred nonparametrically
2) avoid explicit label regularization
3) spatially-adaptive tissue modeling
4) nonparametric modeling


Handling noise

solid line = our method

Handling bias / inhomogeneity / nonuniformity

Validation for segmenting tissues

Validation for delineating the inner cortical-surface
Related Works
Brain MRI tissue classification based on local Markov random fields
J Tohka, ID Dinov, DW Shattuck, AW Toga
Magnetic resonance imaging 2010

M. Yan and J. Karp
An adaptive Bayesian approach to three-dimensional MR brain segmentation
In Proc. Information Processing in Medical Imaging 1995, pp. 201-213

T. Kapur, W. E. L. Grimson, W. M. Wells, and R. Kikinis
Segmentation of brain tissue from magentic resonance images
Medical Image Analysis 1996, 1:109-127

W. M. Wells, W. E. L. Grimson, R. Kikinis, and F. A. Jolesz
Adaptive segmentation of MRI data
IEEE Trans. Medical Imaging 1996, 15(4):429-443

K. V. Leemput, F. Maes, D. Vandermeulen, and P. Seutens
Automated model-based tissue classification of MR images of the brain
IEEE Trans. Med. Imaging 1999, 18:897-908

D. L. Pham, J. L. Prince
An adaptive fuzzy segmentation algorithm for three-dimensional magnetic resonance images
Proc. Information Processing in Medical Imaging 1999, pp. 140-153

Y. Zhang, M. Brady, and S. Smith
Segmentation of brain MR images through a hidden Markov random field model and the expectation maximization algorithm
IEEE Trans. Med. Imaging 2001, 20:45-57

H. Greenspan, A. Ruf , J. Goldberger
Constrained Gaussian mixture model framework for automatic segmentation of MR brain images
IEEE Trans. Med. Imaging 2006, 25(9):1233-1245

Suyash P. Awate, Hui Zhang , James C. Gee
A Fuzzy, Nonparametric Segmentation Framework for DTI and MRI Analysis: With Applications to DTI-Tract Extraction
IEEE Trans. Medical Imaging 2007, 26(11):1525-1536